产品详情
产品名称CES4A Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification
应用IHC
种属反应性Human
特异性The antibody detects endogenous levels of total CES4A protein.
免疫原类型peptide
免疫原描述Synthetic peptide of human CES4A
基因/蛋白名称CES4A
标记Unconjugated
别名CES6; CES8
数据库入口号Swiss-Prot#: Q5XG92
NCBI Gene ID: 283848
Uniprot
Q5XG92
浓度0.5mg/ml
配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
保存Store at -20˚C
应用详情
Immunohistochemistry: 1: 20-100
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CES4A Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They also participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene, also called CES6, encodes a secreted enzyme, and may play a role in the detoxification of drugs and xenobiotics in neural and other tissues of the body and in the cerebrospinal fluid. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature and/or biological validity of some variants have not been determined.
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et al,Carboxylesterase 4A Inhibits the Malignant Biological Behavior of Nasopharyngeal Carcinoma via the PI3K/AKT Pathway.
, (2025),
PMID:
39912257
Yes
