产品详情
产品名称SLC8A1 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification
应用IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous levels of total SLC8A1 protein.
免疫原类型peptide
免疫原描述Synthetic peptide of human SLC8A1
基因/蛋白名称SLC8A1
标记Unconjugated
别名NCX1
数据库入口号Swiss-Prot#: P32418
NCBI Gene ID: 6546
Uniprot
P32418
浓度1mg/ml
配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
保存Store at -20˚C
应用详情
Immunohistochemistry: 1: 20-100
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using SLC8A1 Antibody at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using SLC8A1 Antibody at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200)
In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.
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et al,Identification and study of mood-related biomarkers and potential molecular mechanisms in type 2 diabetes mellitus.
, (2025),
PMID:
39915429
Yes
