产品详情
产品名称CADM2 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification
应用WB IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous levels of total CADM2 protein.
免疫原类型peptide
免疫原描述Synthetic peptide corresponding to residues near the C terminal of human CADM2
基因/蛋白名称CADM2
标记Unconjugated
别名NECL3; IGSF4D; Necl-3; synCAM2; SynCAM 2
数据库入口号Swiss-Prot:Q8N3J6
NCBI Gene ID:253559
NCBI Protein:NP_001161146
Uniprot
Q8N3J6
计算分子量48 kDa
浓度1.2mg/ml
配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:1000-1:5000
Immunohistochemistry: 1: 30-150
Gel: 8%SDS-PAGE
lysate: 20 ¦Ìg, Lane: Human cerebella tissue lysate,
Primary antibody: 46390£¨CADM2 Antibody) at dilution 1/2000
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,
Exposure time: 1 second
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46390(CADM2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 46390(CADM2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200)
This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like domains and a cytosolic protein 4.1 binding site near the C-terminus. Proteins belonging to the protein 4.1 family crosslink spectrin and interact with other cytoskeletal proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
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et al,Genome-Wide Profiling Reveals HPV Integration Pattern and Activated Carcinogenic Pathways in Penile Squamous Cell Carcinoma
, (2021),
PMID:
34885212
Yes
