产品详情
产品名称EEPD1 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification
应用WB, IHC
种属反应性Human
特异性The antibody detects endogenous levels of total EEPD1 protein.
免疫原类型peptide
免疫原描述Synthetic peptide of human EEPD1
基因/蛋白名称EEPD1
标记Unconjugated
别名HSPC107
数据库入口号Swiss-Prot#:Q7L9B9
NCBI Gene ID:80820
Gene Accssion:NP_085139
Uniprot
Q7L9B9
计算分子量63 kDa
浓度0.7mg/ml
配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
保存Store at -20C
应用详情
Western blotting:1:200-1000
Immunofluorescence:1: 20-100
The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 47092(EEPD1 Antibody) at dilution 1/20. (Original magnification: ?00)
Gel: 8%SDS-PAGE
Lysate: 40 μg, Lane 1-3: PC-3 cell, Human cerebrum tissue, 231 cell lysates
Primary antibody:EEPD1 Antibody at dilution 1/300
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 30 seconds
EEPD1(endonuclease/exonuclease/phosphatase family domain containing 1), also known as HSPC107, is a 569 amino acid protein that contains one HhH domain. A significant decrease in the relative transcriptional level of EEPD1 is induced by long-term heat stress exposure. Conversely, EEPD1 is up-regulated in bovine adipogenic processes related to intramuscular pre-adipocyte differentiation. Encoded by a gene that maps to human chromosome 7p14.2, EEPD1 plays a role in DNA binding and repair. Chromosome 7 makes up about 5% of the human genome and contains 158 million bases encoding more than 1,000 genes. Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome are associated with Chromosome 7.
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et al,Super-enhancer-associated EEPD1 facilitates EMT-mediated metastasis by regulating the PI3K/AKT/mTOR pathway in gastric cancerInBiochem Biophys Res CommunOn2023 Dec 31byYong Jin?1,?Ying Xia et al..PMID:?37976838
, (2023),
PMID:
37976838
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