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位置： 首页 > 鼠单克隆抗体 > CD31/PECAM-1 Antibody

CD31/PECAM-1 Antibody #48124

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产品名称CD31/PECAM-1 Antibody

克隆号7-A1

来源种属Mouse

纯化Peptide affinity purified

应用WB, ICC/IF, IHC, FC

种属反应性Human

免疫原描述Synthetic peptide (KLH-coupled) within C-terminal residues of human CD31.

标记Unconjugated

别名Adhesion molecule antibody
CD31 antibody
CD31 antigen antibody
CD31 EndoCAM antibody
EndoCAM antibody
FLJ34100 antibody
FLJ58394 antibody
GPIIA antibody
GPIIA' antibody
PECA1 antibody
PECA1_HUMAN antibody
Pecam 1 antibody
PECAM 1 CD31 EndoCAM antibody
PECAM antibody
PECAM-1 antibody
Pecam1 antibody
Platelet and endothelial cell adhesion molecule 1 antibody
Platelet endothelial cell adhesion molecule antibody
Platelet/endothelial cell adhesion molecule 1 antibody

数据库入口号Swiss-Prot#:P16284

Uniprot P16284

计算分子量82kDa(Observed: 130 kDa)

配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

保存Store at -20˚C

应用详情

WB: 1:1,000-5,000
IHC: 1:50-1:200
ICC: 1:50-1:200

FC:1:50-1:100

Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play an important role in embryogenesis and development. Neuronal cell adhesion molecule (NCAM) expression is observed in a variety of human tumors including neuroblastomas, rhabdomyosarcomas, Wilms’ tumors, Ewing’s sarcomas and some primitive myeloid malignancies. The intracellular adhesion molecule-1 (ICAM-1), also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily. PECAM-1 (platelet/endothelial cell adhesion molecule-1), also referred to as CD31, is a glycoprotein expressed on the cell surfaces of monocytes, neutrophils, platelets and a subpopulation of T cells. VCAM-1 (vascular cell adhesion molecule-1) was first identified as an adhesion molecule induced on human endothelial cells by inflammatory cytokines such as IL-1, tumor necrosis factor (TNF) and lipopolysaccharide (LPS). The KALIG gene encodes a nerve cell adhesion molecule (NCAM)-like protein and is deleted in 66% of patients with Kallmann’s syndrome, anosmia with secondary hypogonadism.

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操作手册

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu人
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk猴
  • Rb兔
  • B牛
  • D狗
  • P猪
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk鸡
;

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