产品详情
产品名称Iba1 Antibody
来源种属Mouse
纯化ProA affinity purified
应用WB;IF;IHC;FC;IP
种属反应性Human;Mouse;Rat
免疫原描述peptide
标记Unconjugated
别名AIF 1 antibody
AIF-1 antibody
Aif1 antibody
AIF1 protein antibody
AIF1_HUMAN antibody
Allograft inflammatory factor 1 antibody
Allograft inflammatory factor 1 splice variant G antibody
allograft inflammatory factor-1 splice variant Hara-1 antibody
balloon angioplasty responsive transcription antibody
BART 1 antibody
G1 antibody
G1 putative splice variant of allograft inflamatory factor 1 antibody
IBA 1 antibody
IBA1 antibody
interferon gamma responsive transcript antibody
Interferon responsive transcript 1 antibody
interferon responsive transcript factor 1 antibody
Ionized calcium binding adapter molecule 1 antibody
Ionized calcium-binding adapter molecule 1 antibody
ionized calcium-binding adapter molecule antibody
IRT 1 antibody
IRT1 antibody
Microglia response factor antibody
MRF1 antibody
Protein g1 antibody
数据库入口号Swiss-Prot#:P55008
Uniprot
P55008
计算分子量17kDa
配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
保存Store at -20˚C
应用详情
WB 1:500-2000; IHC 1:200-1000; IF 1:100-500;FC 1:200-1:1,000 ;IP 1:25-500
Ionized calcium-binding adapter molecule 1 (Iba1), also known as allograft inflammatory factor-1 (AIF-1), is a 147 amino acid cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. Iba1, containing two EF domains, is induced by cytokines and interferons. In an unstimulated state, Iba1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding Iba1 maps to chromosome 6p21.33 and resides in the tumor necrosis factor (TNF) cluster of genes located in the region represented by the human major histocompatibility complex (MHC).
Yes
