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位置： 首页 > 鼠单克隆抗体 > KDR / VEGFR-2 Antibody

KDR / VEGFR-2 Antibody #48311

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产品名称KDR / VEGFR-2 Antibody

克隆号1G1

来源种属Mouse

纯化ProA affinity purified

应用WB, IP, IF, IHC(P)

种属反应性Human;Mouse;Rat

免疫原描述Amino acids 1158-1345 mapping at the C-terminus of the Flk-1 of mouse origin.

标记Unconjugated

别名CD309 antibody
CD309 antigen antibody
EC 2.7.10.1 antibody
Fetal liver kinase 1 antibody
FLK-1 antibody
FLK1 antibody
FLK1, mouse, homolog of antibody
Kdr antibody
Kinase insert domain receptor (a type III receptor tyrosine kinase) antibody
Kinase insert domain receptor antibody
KRD1 antibody
Ly73 antibody
Protein tyrosine kinase receptor FLK1 antibody
Protein-tyrosine kinase receptor flk-1 antibody
soluble VEGFR2 antibody
Tyrosine kinase growth factor receptor antibody
Vascular endothelial growth factor receptor 2 antibody
VEGFR 2 antibody
VEGFR antibody
VEGFR-2 antibody
VEGFR2 antibody
VGFR2_HUMAN antibody

数据库入口号Swiss-Prot#:P35968

Uniprot P35968

计算分子量200kDa

配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

保存Store at -20˚C

应用详情

WB: 1:100-1:1,000
IHC: 1:50-1:500

IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)

Western blot analysis of Flk-1 expression in non-transfected (A) and mouse Flk-1 transfected (B) 293T whole cell lysates.
Western blot analysis of Flk-1 expression in VEGF-treated HUV-EC-C whole cell lysate.

Three cell membrane receptor tyrosine kinases, Flt (also designated VEGF-R1), Flk-1 (also designated VEGF-R2) and Flt-4, putatively involved in the growth of endothelial cells, are characterized by the presence of seven immunoglobulinlike sequences in their extracellular domain. These receptors exhibit high degrees of sequence relatedness to each other as well as lesser degrees of relatedness to the class III receptors including CSF-1/Fms, PDGR, SLFR/Kit and Flt-3/Flk-2. Two members of this receptor class, Flt-1 and Flk-1, have been shown to represent high affinity receptors for vascular endothelial growth factors (VEGFs). On the basis of structural similarity to Flt and Flk-1, it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.

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操作手册

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu人
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk猴
  • Rb兔
  • B牛
  • D狗
  • P猪
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk鸡
;

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