产品详情
产品名称BDNF Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Peptide affinity purified
应用WB, ICC, IHC
种属反应性Human;Mouse;Rat
免疫原描述This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to the N-terminal of human BNDF
标记Unconjugated
别名Abrineurin antibody
ANON2 antibody
BDNF antibody
BDNF_HUMAN antibody
Brain Derived Neurotrophic Factor antibody
Brain-derived neurotrophic factor antibody
BULN2 antibody
MGC34632 antibody
Neurotrophin antibody
数据库入口号Swiss-Prot#:P23560
Uniprot
P23560
计算分子量28kDa
配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
保存Store at -20˚C
应用详情
WB: 1:500
IHC: 1:200
ICC: 1:200
Western blot analysis of BDNF on different cell lysates using anti-BDNF antibody at 1/500 dilution. Positive control: Lane 1: A172 Lane 2: SHG-44 Lane3: Mouse heart Lane 4: Mouse brain
Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-BDNF antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-BDNF antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-BDNF antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-BDNF antibody. Counter stained with hematoxylin.
ICC staining of BNDF in SHG-44 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Brain-derived neurotrophic factor, also known as BDNF, is a member of the "neurotrophin" family of growth factors, which are related to the canonical "Nerve Growth Factor", NGF. BDNF acts on certain neurons of the central nervous system and the peripheral nervous system, helping to support the survival of existing neurons, and encourage the growth and differentiation of new neurons and synapses. BDNF is actually found in a range of tissue and cell types, not just in the brain. It is also expressed in the retina, the central nervous system, motor neurons, the kidneys, and the prostate. Various studies have shown possible links between BDNF and conditions such as depression, bipolar disorder,schizophrenia, obsessive-compulsive disorder, Alzheimer's disease, Huntington's disease, Rett syndrome, and dementia, as well as anorexia nervosa and bulimia nervosa.
如果您使用该产品48503发表了文章，请通知我们，让我们可以引用您的文献。
et al,Classical prescription Daqinjiao decoction inhibit cerebral ischemia/reperfusion induced necroptosis and ferroptosis through multiple mechanisms.
, (2025),
PMID:
39736347
Yes
