产品详情
产品名称ZO1 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Peptide affinity purified
应用ICC, IHC
种属反应性Human;Mouse;Rat
免疫原描述peptide
标记Unconjugated
别名Tight junction protein 1 antibody Tight junction protein ZO-1 antibody Tight junction protein ZO1 antibody TJP1 antibody zo-1 antibody Zo1 antibody ZO1_HUMAN antibody Zona occludens 1 antibody Zona occludens 1 protein antibody Zona occludens protein 1 antibody Zonula occludens 1 protein antibody Zonula occludens protein 1 antibody
数据库入口号Swiss-Prot#:Q07157
Uniprot
Q07157
配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
保存Store at -20˚C
应用详情
IHC: 1:200
ICC: 1:200
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-ZO1 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-ZO1 antibody. Counter stained with hematoxylin.
ICC staining ZO1 in MCF-7 cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Tight junction protein ZO-1 is a protein that in humans is encoded by the TJP1 gene. This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. ZO1 plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.
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et al,Lipopolysaccharide-Induced Chorioamnionitis Induces Fetal Intestinal Injury and Affects Gut Colonization in Rats
, (2020),
PMID:
et al,Bacterial endotoxin-induced maternal inflammation leads to fetal intestinal injury and affects microbial colonization in the neonatal period. In J Matern Fetal Neonatal Med
on 2021 May 31 by Qingmei Huang, Siliang Lu,et al..PMID:34058958
, (2021),
PMID:
34058958
Yes
