产品详情
产品名称Cytokeratin 5 Rabbit mAb
来源种属Recombinant Rabbit
克隆性Monoclonal antibody
纯化ProA affinity purified
应用WB, IHC
种属反应性Human;Mouse
免疫原描述A synthesized peptide derived from human Cytokeratin 5
标记Unconjugated
别名58 kDa cytokeratin antibody
CK-5 antibody
CK5 antibody
Cytokeratin-5 antibody
Cytokeratin5 antibody
DDD antibody
DDD1 antibody
EBS2 antibody
epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types antibody
K2C5_HUMAN antibody
K5 antibody
keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types) antibody
Keratin 5 antibody
Keratin antibody
keratin complex 2, basic, gene 5 antibody
keratin, type II cytoskeletal 5 antibody
Keratin-5 antibody
Keratin5 antibody
KRT 5 antibody
Krt5 antibody
KRT5A antibody
type II cytoskeletal 5 antibody
Type-II keratin Kb5 antibody
数据库入口号Swiss-Prot#:P13647
Uniprot
P13647
计算分子量62 kDa
配方Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
WB: 1:1,000
IHC: 1:50-1:200
Western blot analysis of Cytokeratin 5 on A431 cell lysates using anti-Cytokeratin 5 at 1/500 dilution.
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Cytokeratin 5 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-Cytokeratin 5 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human brest cancer tissue using anti-Cytokeratin 5 antibody. Counter stained with hematoxylin.
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratin 5 is expressed in normal basal cells. Mutations of the cytokeratin 5 gene (KRT5) have been shown to result in the autosomal dominant disorder epidermolysis bullosa (EB).
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