产品详情
产品名称CD20 Rabbit mAb
克隆号SY12-01
来源种属Recombinant Rabbit
克隆性 Monoclonal antibody
纯化ProA affinity purified
应用WB, IHC, IP
种属反应性Hu, Monkey
免疫原描述recombinant protein
标记Unconjugated
别名APY antibody
ATOPY antibody
B lymphocyte antigen CD20 antibody
B Lymphocyte Cell Surface Antigen B1 antibody
B-lymphocyte antigen CD20 antibody
B-lymphocyte cell-surface antigen B1 antibody
B-lymphocyte surface antigen B1 antibody
B1 antibody
Bp 35 antibody
Bp35 antibody
CD 20 antibody
CD20 antibody
CD20 antigen antibody
CD20 receptor antibody
CD20_HUMAN antibody
CVID5 antibody
Fc epsilon receptor I beta chain antibody
Fc Fragment of IgE high affinity I receptor for beta polypeptide antibody
FCER1B antibody
High affinity immunoglobulin epsilon receptor subunit beta antibody
IgE Fc receptor subunit beta antibody
IGEL antibody
IGER antibody
IGHER antibody
LEU 16 antibody
LEU16 antibody
leukocyte surface antigen Leu 16 antibody
Leukocyte surface antigen Leu-16 antibody
Ly44 antibody
Membrane spanning 4 domains A1 antibody
Membrane spanning 4 domains subfamily A member 2 antibody
Membrane-spanning 4-domains subfamily A member 1 antibody
MS4A1 antibody
MS4A2 antibody
S7 antibody
数据库入口号Swiss-Prot#:P11836
Uniprot
P11836
计算分子量33 kDa
配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
保存Store at -20˚C
应用详情
WB: 1:1,000-5,000
IHC: 1:50-1:200
Western blot analysis of CD20 on Raji cell lysates using anti-CD20 antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD20 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD20 antibody. Counter stained with hematoxylin.
CD20 is a leukocyte surface antigen consisting of four transmembrane regions and cytoplasmic N- and C-termini. The cytoplasmic domain of CD20 contains multiple phosphorylation sites, leading to additional isoforms. CD20 is expressed primarily on B cells but has also been detected on both normal and neoplastic T cells. CD20 functions as a calcium-permeable cation channel, and it is known to accelerate the G0 to G1 progression induced by IGF-1. CD20 is activated by the IGF-1 receptor via the alpha subunits of the heterotrimeric G proteins. Activation of CD20 significantly increases DNA synthesis and is thought to involve basic helix-loop-helix leucine zipper transcription factors.
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