产品详情
产品名称CD34 Rabbit mAb
克隆号SI16-01
来源种属Recombinant Rabbit
克隆性Monoclonal antibody
纯化ProA affinity purified
应用WB, ICC/IF, IHC, IP, FC
种属反应性Hu, Ms, Rt, Dog
免疫原描述recombinant protein
标记Unconjugated
别名CD34 antibody CD34 antigen antibody CD34 molecule antibody CD34_HUMAN antibody Cluster designation 34 antibody Hematopoietic progenitor cell antigen CD34 antibody HPCA1 antibody Mucosialin antibody OTTHUMP00000034733 antibody OTTHUMP00000034734 antibody
数据库入口号Swiss-Prot#:P28906
Uniprot
P28906
计算分子量120 kDa
配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
保存Store at -20˚C
应用详情
WB: 1:1,000-1:2,000
IHC: 1:1,000-1:2,000
ICC: 1:50-1:200
FC: 1:1,000
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD34 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-CD34 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-CD34 antibody. Counter stained with hematoxylin.
ICC staining CD34 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining CD34 in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining CD34 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
CD34 is a heavily glycosylated, transmembrane glycoprotein that is expressed on the surface of lymphohematopoietic stem and progenitor cells, small-vessel endothelial cells, embryonic fibroblasts and some cells in fetal and adult nervous tissue. CD34 antigen expression is highest in the most primitive stem cells and is gradually lost as lineage committed progenitors differentiate. The CD34 antigen is also present on capillary endothelial cells and on bone marrow stromal cells. The CD34 cytoplasmic domain has an intracellular domain that contains consensus sites for activated protein kinase C (PKC) phosphorylation as well as serine, threonine and tyrosine phosphorylation consensus sites.
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et al,Identification of Postn+ periosteal progenitor cells with bone regenerative potential. In JCI Insight on 2024 Oct 8 by Bei Yin, Fangyuan Shen, et al..PMID:39377227
, (2024),
PMID:
39377227
Yes
