产品详情
产品名称E Cadherin Rabbit mAb
克隆号SY0287
来源种属Recombinant Rabbit
克隆性 Monoclonal antibody
纯化ProA affinity purified
应用WB, ICC/IF, IHC, IP
种属反应性Human
免疫原描述recombinant protein
标记Unconjugated
别名Arc 1 antibody
CADH1_HUMAN antibody
Cadherin 1 antibody
cadherin 1 type 1 E-cadherin antibody
Cadherin1 antibody
CAM 120/80 antibody
CD 324 antibody
CD324 antibody
CD324 antigen antibody
cdh1 antibody
CDHE antibody
E-Cad/CTF3 antibody
E-cadherin antibody
ECAD antibody
Epithelial cadherin antibody
epithelial calcium dependant adhesion protein antibody
LCAM antibody
Liver cell adhesion molecule antibody
UVO antibody
Uvomorulin antibody
数据库入口号Swiss-Prot#:P12830
Uniprot
P12830
计算分子量97/91 kDa
配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
保存Store at -20˚C
应用详情
WB: 1:1,000
IHC: 1:50-1:200
ICC: 1:50-1:200
FC: 1:50-1:100
Western blot analysis of E Cadherin on MCF-7 (1) and A431 (2) cells lysates using anti-E Cadherin antibody at 1/1,000 dilution.
Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Members of this family of adhesion proteins include rat cadherin K (and its human homolog, cadherin-6), R-cadherin, B-cadherin, E/P cadherin and cadherin-5. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The most distal of these cadherins is thought to be responsible for binding specificity, transmembrane domains and carboxy terminal intracellular domains. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as β-catenin, to regulate cadherin function.
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et al,PD-L1 Expression Is Regulated By NF-κB DurIng EMT SignalIng In Gastric CarcInoma. In Onco Targets Ther on 2019 Nov 25 by Xu D, Li J, et al..PMID:31819504
, (2019),
PMID:
31819504
Yes
