产品详情
产品名称c-Kit Rabbit mAb
克隆号ST04-99
来源种属Recombinant Rabbit
克隆性 Monoclonal antibody
纯化ProA affinity purified
应用WB, IHC
种属反应性Human
免疫原描述recombinant protein
标记Unconjugated
别名C Kit antibody c-Kit antibody c-Kit Ligand antibody CD117 antibody Kit antibody Kit Ligand antibody KIT oncogene antibody KIT proto oncogene receptor tyrosine kinase antibody KIT_HUMAN antibody Mast cell growth factor receptor antibody Mast/stem cell growth factor receptor Kit antibody MGF antibody p145 c-kit antibody PBT antibody Piebald trait protein antibody Proto oncogene c Kit antibody Proto oncogene tyrosine protein kinase Kit antibody Proto-oncogene c-Kit antibody SCF Receptor antibody SCFR antibody soluble KIT variant 1 antibody Steel Factor Receptor antibody Stem cell factor receptor antibody tyrosine protein kinase Kit antibody Tyrosine-protein kinase Kit antibody v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog antibody v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein antibody v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog antibody
数据库入口号Swiss-Prot#:P10721
Uniprot
P10721
计算分子量110 kDa
配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
保存Store at -20˚C
应用详情
WB: 1:1,000
IHC: 1:50-1:200
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-c-Kit antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-c-Kit antibody. Counter stained with hematoxylin.
The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell proliferation, apoptosis and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto-oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers.
如果您使用该产品48897发表了文章，请通知我们，让我们可以引用您的文献。
Yes
