产品详情
产品名称Cytokeratin 5 Rabbit mAb
克隆号SC62-04
来源种属Recombinant Rabbit
克隆性Monoclonal antibody
纯化ProA affinity purified
应用WB, ICC/IF, IHC
种属反应性Human;Mouse;Rat
免疫原描述recombinant protein
标记Unconjugated
别名58 kDa cytokeratin antibody CK-5 antibody CK5 antibody Cytokeratin-5 antibody Cytokeratin5 antibody DDD antibody DDD1 antibody EBS2 antibody epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types antibody K2C5_HUMAN antibody K5 antibody keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types) antibody Keratin 5 antibody Keratin antibody keratin complex 2, basic, gene 5 antibody keratin, type II cytoskeletal 5 antibody Keratin-5 antibody Keratin5 antibody KRT 5 antibody Krt5 antibody KRT5A antibody type II cytoskeletal 5 antibody Type-II keratin Kb5 antibody
数据库入口号Swiss-Prot#:P13647
Uniprot
P13647
计算分子量62 kDa
配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
保存Store at -20˚C
应用详情
WB: 1:1,000-1:2,000
IHC: 1:50-1:200
ICC: 1:50-1:200
Western blot analysis of Cytokeratin 5 on A431 cells lysates using anti-Cytokeratin 5 antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Cytokeratin 5 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-Cytokeratin 5 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-Cytokeratin 5 antibody. Counter stained with hematoxylin.
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratin 5 is expressed in normal basal cells. Mutations of the cytokeratin 5 gene (KRT5) have been shown to result in the autosomal dominant disorder epidermolysis bullosa (EB).
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