产品详情
产品名称CD38 Rabbit mAb
克隆号SN07-20
来源种属Recombinant Rabbit
克隆性Monoclonal antibody
纯化ProA affinity purified
应用WB, IHC, FC, IF
种属反应性Human
免疫原描述recombinant protein
标记Unconjugated
别名Acute lymphoblastic leukemia cells antigen CD38 antibody ADP ribosyl cyclase 1 antibody ADP ribosyl cyclase antibody ADP ribosyl cyclase/cyclic ADP-ribose hydrolase antibody ADP-ribosyl cyclase 1 antibody ADPRC 1 antibody ADPRC1 antibody cADPr hydrolase 1 antibody CD 38 antibody CD38 antibody CD38 antigen (p45) antibody CD38 antigen antibody CD38 molecule antibody Cd38-rs1 antibody CD38_HUMAN antibody CD38H antibody Cyclic ADP ribose hydrolase antibody Cyclic ADP ribose hydrolase 1 antibody Cyclic ADP-ribose hydrolase 1 antibody EC 3.2.2.5 antibody Ecto nicotinamide adenine dinucleotide glycohydrolase antibody I-19 antibody I19 (mouse) antibody Lymphocyte differentiation antigen CD38 antibody NAD(+) nucleosidase antibody NIM-R5 antigen antibody NIMR5 antigen (mouse) antibody OTTHUMP00000158633 antibody OTTHUMP00000217743 antibody p45 antibody T10 antibody
数据库入口号Swiss-Prot#:P28907
Uniprot
P28907
计算分子量40/50 kDa
配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
保存Store at -20˚C
应用详情
WB: 1:1,000
IHC: 1:50-1:200
FC: 1:1,000
IF: 1:1,000
Western blot analysis of CD38 on different lysates using anti-CD38 antibody at 1/1,000 dilution. Positive control: Lane 1: THP-1 Lane 2: Raji
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD38 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD38 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-CD38 antibody. Counter stained with hematoxylin.
CD38 is a type II integral membrane glycoprotein which is present on early B and T cell lineages and activated B and T cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B cells, mitogen-activated T cells, monocytes and Ig-secreting plasma cells. CD38 acts as a NAD glycohydrolase in T lymphocytes. On hematopoietic cells CD38 induces activation, proliferation, and differentiation of mature T and B cells and mediates apoptosis of myeloid and lymphoid progenitor cells. In addition to acting as a signaling receptor, CD38 is also an enzyme capable of producing several calcium-mobilizing metabolites, including cyclic adenosine diphosphate ribose (cADPR). CD38 also plays a role in maintaining survival of an invariant NK T (iNKT) cell subset that preferentially contributes to the maintenance of immunological tolerance.
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