产品详情
产品名称RUNX2 Rabbit mAb
来源种属Recombinant Rabbit
克隆性Monoclonal antibody
纯化Affinity-chromatography
应用WB;IHC;ICC/IF
种属反应性Human;Mouse;Rat
免疫原描述A synthesized peptide derived from human RUNX2
标记Unconjugated
别名Acute myeloid leukemia 3 protein antibody
Alpha subunit 1 antibody
AML3 antibody
CBF alpha 1 antibody
CBF-alpha-1 antibody
CBFA1 antibody
CCD antibody
CCD1 antibody
Cleidocranial dysplasia 1 antibody
Core binding factor antibody
Core binding factor runt domain alpha subunit 1 antibody
Core binding factor subunit alpha 1 antibody
Core-binding factor subunit alpha-1 antibody
MGC120022 antibody
MGC120023 antibody
Oncogene AML 3 antibody
Oncogene AML-3 antibody
OSF 2 antibody
OSF-2 antibody
OSF2 antibody
Osteoblast specific transcription factor 2 antibody
Osteoblast-specific transcription factor 2 antibody
OTTHUMP00000016533 antibody
PEA2 alpha A antibody
PEA2-alpha A antibody
PEA2aA antibody
PEBP2 alpha A antibody
PEBP2-alpha A antibody
PEBP2A1 antibody
PEBP2A2 antibody
PEBP2aA antibody
PEBP2aA1 antibody
Polyomavirus enhancer binding protein 2 alpha A subunit antibody
Polyomavirus enhancer-binding protein 2 alpha A subunit antibody
Runt domain antibody
Runt related transcription factor 2 antibody
Runt-related transcription factor 2 antibody
RUNX2 antibody
RUNX2_HUMAN antibody
SL3 3 enhancer factor 1 alpha A subunit antibody
SL3-3 enhancer factor 1 alpha A subunit antibody
SL3/AKV core binding factor alpha A subunit antibody
SL3/AKV core-binding factor alpha A subunit antibody
数据库入口号Swiss-Prot#:Q13950
Uniprot
Q13950
配方Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
保存Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.
应用详情
WB 1:1000-1:2000;
IHC 1:100-1:200;
ICC/IF 1:50-1:200
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
Immunohistochemical analysis of paraffin-embedded human colon, using RUNX2 Antibody.
Immunofluorescent analysis of Saos-2 cells, using RUNX2 Antibody.
The mammalian Runt-related transcription factor (RUNX) family comprises three members, RUNX1 (also designated AML-1, PEBP2αB, CBFA2), RUNX2 (also designated AML-3, PEBP2αA, CBFA1, Osf2) and RUNX3 (also designated AML-2, PEBPαC, CBFA3). RUNX family members are DNA-binding proteins that regulate the expression of genes involved in cellular differentiation and cell cycle progression. RUNX2 is essential for skeletal mineralization in that it stimulates osteoblast differentiation of mesenchymal stem cells, promotes chondrocyte hypertrophy and contributes to endothelial cell migration and vascular invasion of developing bones. Regulating RUNX2 expression may be a useful therapeutic tool for promoting bone formation. Mutations in the C-terminus of RUNX2 are associated with cleidocranial dysplasia syndrome, an autosomal-dominant skeletal dysplasia syndrome that is characterized by widely patent calvarial sutures, clavicular hypoplasia, supernumerary teeth, and short stature.
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et al,Nanotherapy for bone repair: milk-derived small extracellular vesicles delivery of icariinInDrug Deliv On2023 DecbyXinxin Yu?1,?Ming Dong et al..PMID: 36714914
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PMID:
36714914
et al,Multifunctional Injectable Bioadhesive with Toll-like Receptor 4 and Myeloid Differentiation Factor 2 Antagonistic Anti-inflammatory Potential for Periodontal Regeneration.
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PMID:
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