产品详情
产品名称Glucagon Rabbit mAb
来源种属Recombinant Rabbit
克隆性Monoclonal
纯化Protein A
应用WB;IHC;IF
种属反应性Human;Mouse;Rat
基因/蛋白名称GCG
标记Unconjugated
别名GCG;Glucagon
数据库入口号P01275
Uniprot
P01275
Gene ID
2641
计算分子量21 kDa
实际分子量21 kDa
配方PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
保存Store at -20℃/1 year
应用详情
IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000
Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-Glucagon antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue using anti-Glucagon antibody. Counter stained with hematoxylin.
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Glucagon antibody.
Immunofluorescence analysis of NIH/3T3 cells, using Glucagon Antibody. The picture on the right is blocked with the synthesized peptide.
Glucagon is a pancreatic hormone that functions as an antagonist to insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels. Glucagon-like peptide-1 (GLP-1), Glucagon-like peptide-2 (GLP-2), VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are members of the glucagon family of hormones. GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior, whereas GLP-2 is a stimulator of intestinal epithelial growth. VIP causes vasodilation resulting in the lowering of blood pressure. PACAP is abundant in the hypothalamus and has been shown to increase the synthesis of several hormones, including growth hormone.
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et al,Pathophysiological characterization of the ApoE-/-;db/db mouse: A model of diabetes and atherosclerosis.
, (2025),
PMID:
39761864
Yes
