产品详情
产品名称RPE65 Rabbit mAb
克隆号JM61-51
来源种属Recombinant Rabbit
克隆性 Monoclonal antibody
纯化ProA affinity purified
应用WB, IP
种属反应性Human;Mouse;Rat
免疫原描述recombinant protein
标记Unconjugated
别名All-trans-retinyl-palmitate hydrolase antibody
LCA 2 antibody
LCA2 antibody
Leber congenital amaurosis antibody
mRPE 65 antibody
mRPE65 antibody
p63 antibody
rd 12 antibody
rd12 antibody
Retinal pigment epithelium specific 61 kDa protein antibody
Retinal pigment epithelium specific 65 kDa protein antibody
Retinal pigment epithelium specific protein antibody
Retinal pigment epithelium specific protein 65kDa antibody
Retinal pigment epithelium-specific 65 kDa protein antibody
Retinitis pigmentosa 20 antibody
Retinoid isomerohydrolase antibody
Retinol isomerase antibody
RP 20 antibody
RP20 antibody
RPE 65 antibody
RPE65 antibody
RPE65_HUMAN antibody
sRPE 65 antibody
sRPE65 antibody
数据库入口号Swiss-Prot#:Q16518
Uniprot
Q16518
计算分子量61 kDa
配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
保存Store at -20˚C
应用详情
WB: 1:1,000-1:2,000
IP: 1:10-1:50
Western blot analysis of RPE65 on mouse eyeball cells lysates using anti-RPE65 antibody at 1/500 dilution.
The retinal pigment epithelium (RPE) is a monolayer simple epithelium in proximity to the outer surface of the retinal photoreceptor cells. Retinal pigment epithelium-specific protein (RPE65) is a 65kDa protein belonging to the beta-carotene dioxygenase family. This protein is important in 11-cis retinal production as well as in visual pigment regeneration. RPE65 is attached to the membrane by a lipid anchor when palmitoylated (membrane form) and soluble when unpalmitoylated. The soluble form of the protein binds vitamin A. Defects in RPE65 causes autosomal dominant retinitis pigmentosa and/or Leber congenital amaurosis type 2.
如果您使用该产品49495发表了文章，请通知我们，让我们可以引用您的文献。
et al,Suppressing endoplasmic reticulum stress-related autophagy attenuates retinal light injury. In Aging (Albany NY) on 2020 Aug 28 by Jing-Yao Song, Bin Fan,et al..PMID: 32858529
, (2020),
PMID:
32858529
Yes
