产品详情
产品名称Caspase 9 Rabbit mAb
克隆号S09-4C4
来源种属Recombinant Rabbit
克隆性Monoclonal antibody
亚型Rabbit IgG
纯化Affinity Purified
应用WB
种属反应性Human;Mouse
免疫原描述Recombinant protein of human Caspase-9
标记Unconjugated
别名CASP 9; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3; ICE-like apoptotic protease 6; ICE-LAP6; Caspase-9 subunit p35; Caspase-9 subunit p10; CASP9; MCH6;
数据库入口号Swiss-Prot:P55211
GeneID:842
Uniprot
P55211
Gene ID
842
计算分子量Calculated MW: 46 kDa; Observed MW: 46 kDa
配方50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
保存Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.
应用详情
WB: 1/1000;
Western blot detection of Caspase-9 in 3T3,Hela cell lysates using Caspase-9 Rabbit mAb(1:1000 diluted).Predicted band size:46kDa.Observed band size:46kDa.
Swiss-Prot Acc.P55211.Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
如果您使用该产品52085发表了文章，请通知我们，让我们可以引用您的文献。
et al,CD155 Cooperates with PD-1/PD-L1 to Promote Proliferation of Esophageal Squamous Cancer Cells via PI3K/Akt and MAPK Signaling Pathways. In Cancers (Basel) on 2022 Nov 15 by Xiyang Tan, Jie Yang, et al..PMID:36428703
, (2022),
PMID:
36428703
Yes
