产品详情
产品名称CD147 Rabbit mAb
克隆号S04-5B3
来源种属Recombinant Rabbit
克隆性Monoclonal antibody
亚型IgG
纯化Affinity Purified
应用WB IHC
种属反应性Human;Mouse;Rat
免疫原描述A synthetic peptide of human CD147
标记Unconjugated
别名OK; 5F7; TCSF; CD147; EMMPRIN
数据库入口号Swiss-Prot:P35613
GeneID:682
Uniprot
P35613
Gene ID
682
计算分子量Calculated MW:42 kDa,Observed MW:50 kDa
配方50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
保存Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.
应用详情
WB: 1/1000-1/5000 IHC: 1/50-1/200
Western blot detection of CD147 in Hela,Ramos cell lysates using CD147 Rabbit mAb(1:1000 diluted).Predicted band size:42kDa.Observed band size:42kDa.
Immunohistochemistry of CD147 in paraffin-embedded Human colon cancer tissue using CD147 Rabbit mAb at dilution 1/50
Essential for normal retinal maturation and development (By similarity).Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors (PubMed:25957687).In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors (PubMed:25957687).May act as a potent stimulator of IL6 secretion in multiple cell lines that include monocytes (PubMed:21620857).
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et al,Effect of silencing CD147 on glycolysis in prostate cancer LNCaP cells
, (2023),
PMID:
Yes
