产品详情
产品名称CD4 Rabbit Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IF
种属反应性Human;Mouse;Rat
免疫原描述Recombinant fusion protein of human CD4 (NP_000607.1).
标记Unconjugated
别名CD4;CD4mut
数据库入口号Swiss Prot:P01730
GeneID:920
Uniprot
P01730
计算分子量51kDa
实际分子量51kDa
配方Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IF 1:50 - 1:200
Immunohistochemistry of paraffin-embedded rat thymus using CD4 at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded mouse thymus using CD4 at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded mouse spleen using CD4 at dilution of 1:200 (40x lens).
Western blot analysis of extracts of U-937 cells, using CD4 at 1:500 dilution.
This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
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et al,CD155 Cooperates with PD-1/PD-L1 to Promote Proliferation of Esophageal Squamous Cancer Cells via PI3K/Akt and MAPK Signaling Pathways. In Cancers (Basel) on 2022 Nov 15 by Xiyang Tan, Jie Yang, et al..PMID:36428703
, (2022),
PMID:
36428703
Yes
