产品详情
产品名称WNT5A Rabbit Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB;IHC;IF
种属反应性Human;Mouse;Rat
免疫原描述A synthetic peptide of human WNT5A (NP_003383.2).
标记Unconjugated
别名hWNT5A;Wnt5a;WNT5A
数据库入口号Swiss Prot:P41221
GeneID:7474
Uniprot
P41221
计算分子量40kDa/42kDa
实际分子量42kDa
配方Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB: 1:500 - 1:1000 IHC: 1:100 - 1:500 IF: 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using WNT5A at 1:3000 dilution.
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome. Alternate splicing results in multiple transcript variants.
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et al,Effect of Yiguan Decoction on the efficacy of M1 bone marrow-derived macrophages in treatment of liver cirrhosis rats and its mechanism
, (2024),
PMID:
Yes
