产品详情
产品名称VEGF Receptor 1 Rabbit Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC
种属反应性Human;Mouse;Rat
免疫原描述Recombinant fusion protein of human VEGF Receptor 1 (NP_001153392.1).
标记Unconjugated
别名FLT;FLT-1;VEGFR-1;VEGFR1;FLT1
数据库入口号Swiss Prot:P17948
GeneID:2321
Uniprot
P17948
计算分子量39kDa/41kDa/52- 82kDa/150kDa
实际分子量151kDa
配方Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:100
Western blot analysis of extracts of various cell lines, using VEGF Receptor 1 at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded rat spleen using FLT1 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human placenta using FLT1 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse spleen using FLT1 at dilution of 1:100 (40x lens).
This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.
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et al,Correlation between N-terminal pro-atrial natriuretic peptide, corin, and target organ damage in hypertensive disorders of pregnancy. In J Clin Hypertens (Greenwich) on 2022 May by Wei Zhang, Ying Zhou, et al..PMID:35199942
, (2022),
PMID:
35199942
Yes
