产品详情
产品名称WIF1 Rabbit Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC
种属反应性Human;Mouse;Rat
免疫原描述Recombinant fusion protein of human WIF1 (NP_009122.2).
标记Unconjugated
别名WIF1;WIF-1
数据库入口号Swiss Prot:Q9Y5W5
GeneID:11197
Uniprot
Q9Y5W5
计算分子量41kDa
实际分子量42kDa
配方Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:2000 - 1:5000
IHC 1:50 - 1:200
Western blot analysis of extracts of mouse heart, using WIF1 at 1:1000 dilution.
The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers.
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et al,Potential role of DKK3 and WIF1 in prostate cancer: bioinformatics and clinical analysis
, (2025),
PMID:
40864208
Yes
