产品详情
产品名称ATF3 Rabbit Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC,IF
种属反应性Human;Mouse;Rat
免疫原描述Recombinant fusion protein of human ATF3 (NP_001665.1).
标记Unconjugated
别名ATF3
数据库入口号Uniprot:P18847
GeneID:467
Uniprot
P18847
Gene ID
467
计算分子量12kDa/13kDa/14kDa/15kDa/20kDa
实际分子量23KDa/24KDa
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of 293T cells, using ATF3 antibody.
Western blot analysis of extracts of RAW264.7 cells, using ATF3 antibody.
Immunohistochemistry of paraffin-embedded human lung cancer using ATF3 Rabbit pAb.
Immunofluorescence analysis of U-2 OS cells using ATF3 antibody.
This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes.
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et al,CDK4/6i enhances the antitumor effect of PD1 antibody by promoting TLS formation in ovarian cancer In HeliyonOn2023 Sep 14byWangyou Feng , Dongbo Jiang et al..PMID:37809574
, (2023),
PMID:
37809574
Yes
