产品详情
产品名称UNC5B Rabbit Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IF
种属反应性Human;Mouse;Rat
免疫原描述Recombinant fusion protein of human UNC5B (NP_734465.2).
标记Unconjugated
别名UNC5B;UNC5H2;p53RDL1
数据库入口号Swiss Prot:Q8IZJ1
GeneID:219699
Uniprot
Q8IZJ1
计算分子量102kDa/103kDa
实际分子量104kDa
配方Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IF 1:50 - 1:100
Western blot analysis of extracts of various cell lines, using UNC5B at 1:1000 dilution.
This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene.
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et al,Identification of UNC5B as a novel aggressive biomarker for osteosarcoma based on basement membrane genes
, (2024),
PMID: