产品详情
产品名称MYH2 Rabbit Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB;IF/ICC
种属反应性Human;Mouse;Rat
免疫原描述A synthetic peptide of human MYH2 (NP_001093582.1).
标记Unconjugated
别名MYH2;IBM3;MYH2A;MYHSA2;MYHas8;MYPOP;MyHC-2A;MyHC-IIa;myosin-2
数据库入口号Swiss Prot:Q9UKX2
GeneID:4620
Uniprot
Q9UKX2
计算分子量223 kDa
实际分子量250 kDa
配方PBS with 0.05% proclin300, 50% glycerol, pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500-1:1000;
IF 1:50-1:200
Western blot analysis of lysates from Rat skeletal muscle, using MYH2 at 1:1000 dilution
Western blot analysis of lysates from Mouse skeletal muscle, using MYH2 at 1:1000 dilution.
Western blot analysis of lysates from U-2 OS cells using MYH2 at 1:1000 dilution
Immunofluorescence analysis of paraffin-embedded mouse skeletal muscle using MYH2 at dilution of 1:50 (40x lens).
Immunofluorescence analysis of paraffin-embedded rat skeletal muscle using MYH2 at dilution of 1:50 (40x lens).
Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in inclusion body myopathy-3. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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et al,GLP-1RA Liraglutide and Semaglutide Improves Obesity-Induced Muscle Atrophy via SIRT1 PathwayInDiabetes Metab Syndr ObesOn2023 Aug 15byJie Xiang?1,?Liyan Qin et al..PMID: 37602204
, (2023),
PMID:
37602204
Yes
