产品详情
产品名称CCL8 Rabbit Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC,IF
种属反应性Human;Mouse
免疫原描述Recombinant fusion protein of human CCL8 (NP_005614.2).
标记Unconjugated
别名CCL8;HC14;MCP-2;MCP2;SCYA10;SCYA8
数据库入口号Swiss Prot:P80075
GeneID:6355
Uniprot
P80075
计算分子量11kDa
配方Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:100
Immunohistochemistry of paraffin-embedded human liver using CCL8 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human prostate cancer using CCL8 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human stomach using CCL8 at dilution of 1:100 (40x lens).
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.
如果您使用该产品55062发表了文章，请通知我们，让我们可以引用您的文献。
et al,Tumor-initiating cells escape tumor immunity via CCL8 from tumor-associated macrophages in mice.
, (2025),
PMID:
39774471
Yes
