产品详情
产品名称Recombinant mouse Apoptosis regulator Bcl-2 protein
来源种属E.coli
基因/蛋白名称BCL2
数据库入口号Uniprot ID: P10417
Uniprot
P10417
计算分子量26.8kD
配方20mM Tris-HCl based buffer,pH8.0
保存Store at -20˚C, for extended storage, conserve at -20˚C or -80˚C. Repeated freezing and thawing is not recommended. Store working aliquots at 4˚C for up to one week.
Target种属MOUSE
Target长度Partial of the full length of 1-236aa, 5-205aa
应用详情
Purity: Greater than 90% as determined by SDS-PAGE.
Suppresses apoptosis in a variety of cell systs including factor-dependent lymphohatopoietic and neural cells. Regulates cell death by controlling the mitochondrial mbrane permeability. Appears to function in a feedback loop syst with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
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