产品详情
产品名称Recombinant human Brain-derived neurotrophic factor
来源种属E.coli
基因/蛋白名称BDNF
别名Abrineurin
数据库入口号Uniprot ID: P23560
Uniprot
P23560
计算分子量29.5kD
配方20mM Tris-HCl based buffer,pH8.0
保存Store at -20˚C, for extended storage, conserve at -20˚C or -80˚C. Repeated freezing and thawing is not recommended. Store working aliquots at 4˚C for up to one week.
Target种属HUMAN
Target长度Full length, 129-247aa
应用详情
Purity: Greater than 90% as determined by SDS-PAGE.
During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systs. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is phasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
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15-30工作日
