产品详情
产品名称Recombinant human Bone morphogenetic protein receptor type-1A
来源种属E.coli
基因/蛋白名称BMR1A
别名Activin receptor-like kinase 3 ;ALK-3Serine/threonine-protein kinase receptor R5 ;SKR5; CD292
数据库入口号Uniprot ID: P36894
Uniprot
P36894
计算分子量56.57kD
配方20mM Tris-HCl based buffer,pH8.0
保存Store at -20˚C, for extended storage, conserve at -20˚C or -80˚C. Repeated freezing and thawing is not recommended. Store working aliquots at 4˚C for up to one week.
Target种属HUMAN
Target长度Full length of Cytoplasmic, 177-532aa
应用详情
Purity: Greater than 90% as determined by SDS-PAGE.
On ligand binding, forms a receptor complex consisting of two type II and two type I transmbrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4. Positively regulates chondrocyte differentiation through GDF5 interaction .
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15-30工作日
