产品详情
产品名称Recombinant human Anaphase-promoting complex subunit 15
来源种属E.coli
基因/蛋白名称APC15
数据库入口号Uniprot ID: P60006
Uniprot
P60006
计算分子量41.7kD
配方20mM Tris-HCl based buffer,pH8.0
保存Store at -20˚C, for extended storage, conserve at -20˚C or -80˚C. Repeated freezing and thawing is not recommended. Store working aliquots at 4˚C for up to one week.
Target种属HUMAN
Target长度Full length, 1-121aa
应用详情
Purity: Greater than 90% as determined by SDS-PAGE.
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating in the responsiveness of the spindle assbly checkpoint. Also required for degradation of CDC20.
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15-30工作日
