产品详情
产品名称Recombinant human C-C motif chemokine 21
来源种属E.coli
基因/蛋白名称CCL21
别名6Ckine;Beta-chemokine exodus-2;Secondary lymphoid-tissue chemokine ;SLC;Small-inducible cytokine A21
数据库入口号Uniprot ID: O00585
Uniprot
O00585
计算分子量39.6kD
配方20mM Tris-HCl based buffer,pH8.0
保存Store at -20˚C, for extended storage, conserve at -20˚C or -80˚C. Repeated freezing and thawing is not recommended. Store working aliquots at 4˚C for up to one week.
Target种属HUMAN
Target长度Full length, 24-134aa
应用详情
Purity: Greater than 90% as determined by SDS-PAGE.
Inhibits hopoiesis and stimulates chotaxis. Chotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
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