产品详情
产品名称Recombinant human Monocyte differentiation antigen CD14
来源种属E.coli
基因/蛋白名称CD14
别名Myeloid cell-specific leucine-rich glycoprotein; CD14
数据库入口号Uniprot ID: P08571
Uniprot
P08571
计算分子量62.5kD
配方20mM Tris-HCl based buffer,pH8.0
保存Store at -20˚C, for extended storage, conserve at -20˚C or -80˚C. Repeated freezing and thawing is not recommended. Store working aliquots at 4˚C for up to one week.
Target种属HUMAN
Target长度Monocyte differentiation antigen CD14, membrane-bound form, 20-345aa
应用详情
Purity: Greater than 90% as determined by SDS-PAGE.
In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
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15-30工作日
