产品详情
产品名称Recombinant human CD44 antigen
来源种属E.coli
基因/蛋白名称CD44
别名CDw44Epican;Extracellular matrix receptor III ;ECMR-IIIGP90 lymphocyte homing/adhesion receptor;HUTCH-IHeparan sulfate proteoglycan;Hermes antigen;Hyaluronate receptor;Phagocytic glycoprotein 1 ;PGP-1;Phagocytic glycoprotein I ;PGP-I; CD44
数据库入口号Uniprot ID: P16070
Uniprot
P16070
计算分子量80.1kD
配方20mM Tris-HCl based buffer,pH8.0
保存Store at -20˚C, for extended storage, conserve at -20˚C or -80˚C. Repeated freezing and thawing is not recommended. Store working aliquots at 4˚C for up to one week.
Target种属HUMAN
Target长度Extracellular domain of Isoform 4, 21-606aa
应用详情
Purity: Greater than 90% as determined by SDS-PAGE.
Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hatopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
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15-30工作日
