产品详情
产品名称Recombinant mouse Complement factor B
来源种属E.coli
基因/蛋白名称CFAB
别名C3/C5 convertaseGlycine-rich beta glycoprotein ;GBGPBF2;Properdin factor B
数据库入口号Uniprot ID: P00751
Uniprot
P00751
计算分子量86.9kD
配方20mM Tris-HCl based buffer,pH8.0
保存Store at -20˚C, for extended storage, conserve at -20˚C or -80˚C. Repeated freezing and thawing is not recommended. Store working aliquots at 4˚C for up to one week.
Target种属HUMAN
Target长度Full length, 23-761aa
应用详情
Purity: Greater than 90% as determined by SDS-PAGE.
Factor B which is part of the alternate pathway of the complent syst is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complent factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
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15-30工作日
