产品详情
产品名称Cytochrome C Antibody Biotin Conjugated
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Purified by Protein A.
应用WB IHC-P
种属反应性Hu Ms Rt
免疫原描述KLH conjugated synthetic peptide aa 50-89 105 derived from human Cytochrome C
基因/蛋白名称Cytochrome C
标记Biotin
激发/发射波长N A
别名CYC; HCS; THC4; Cytochrome c; CYCS
浓度1mg ml
配方10mM Tris Buffered Saline containing 1% BSA, 50% glycerol and 0.09% sodium azide.
保存 Store at 4C for 12 months.
应用详情
Western blotting: 1:100-1000
Immunohistochemistry1:100-500
Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
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货期15天
