产品详情
产品名称Cytochrome C Antibody FITC Conjugated
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Purified by Protein A.
应用FC;ICC;IF
种属反应性Hu Ms Rt
免疫原描述KLH conjugated synthetic peptide aa 50-89 105 derived from human Cytochrome C
基因/蛋白名称Cytochrome C
标记FITC
激发/发射波长494nm 518nm
别名CYC; HCS; THC4; Cytochrome c; CYCS
浓度1mg ml
配方0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存Shipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
应用详情
Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200
Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
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货期15天
