产品详情
产品名称Caspase 3 Antibody Biotin Conjugated
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Purified by Protein A.
应用WB IHC-P
种属反应性Hu Ms Rt B Goat
免疫原描述KLH conjugated synthetic peptide aa 60-100 277 derived from human Caspase 3(Active)
基因/蛋白名称Caspase-3
标记Biotin
激发/发射波长N A
别名CPP32; SCA-1; CPP32B; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; CASP3
数据库入口号Swiss-Prot#P42574
NCBI Gene ID836
Uniprot
P42574
浓度1mg ml
配方10mM Tris Buffered Saline containing 1% BSA, 50% glycerol and 0.09% sodium azide.
保存 Store at 4C for 12 months.
应用详情
Western blotting: 1:100-1000
Immunohistochemistry1:100-500
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
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货期15天
