产品详情
产品名称P2Y10 Polyclonal Antibody Cy5 Conjugated
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Purified by Protein A.
应用FCM IF(IHC-P)
种属反应性Hu Ms Rt
免疫原描述KLH conjugated synthetic peptide aa 160-210 339 derived from human P2Y10
基因/蛋白名称P2Y10
标记Cy5
激发/发射波长625,650nm 670nm
别名G protein coupled purinergic receptor P2Y10; P2ry10; P2Y like receptor; P2Y purinoceptor 10; P2Y-like receptor; P2Y10; P2Y10_HUMAN; Purinergic receptor P2Y G protein coupled 10; Putative P2Y purinoceptor 10.
数据库入口号Swiss-Prot#:O00398
NCBI Gene ID:27334
Uniprot
O00398
浓度1mg ml
配方Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
保存 Store at 4C for 12 months.
应用详情
FCM:1:20-100
IF:1:50-200
Nucleotides are important extracellular signaling molecules that mediate several events, such as cell proliferation, differentiation, chemotaxis and cytokine release. The P2 receptor family is activated by the binding of nucleotides and is divided into two subfamilies, designated P2X and P2Y. The P2Y receptor family are G protein-coupled receptors that mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C (PLC). To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. P2Y10 (purinergic receptor P2Y, G-protein coupled, 10), also known as P2RY10, is a 339 amino acid multi-pass membrane protein that is thought to act as a receptor for purines coupled to G-proteins. P2Y10 is found at low levels in blood leukocytes and is upregulated during promyelocytic cell differentiation.
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et al,Microbiota metabolite taurodeoxycholic acid maintains intestinal tissue residency of innate lymphoid cells via engagement with P2Y10 receptor
, (2025),
PMID:
40845099
货期15天
