产品详情
产品名称PI3 kinase p85 alpha + gamma (Phospho-Tyr467 + Tyr199) antibody HRP Conjugated
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Purified by Protein A.
应用WB IHC-P IHC-F
种属反应性Hu Ms Rt
免疫原描述KLH conjugated synthetic phosphopeptide aa 176-212 461 derived from human PI3K around the phosphorylation site of p85 alphaTyr467
基因/蛋白名称PI3 kinase p85 alpha + gamma Tyr467 + Tyr199
标记HRP
激发/发射波长N A
别名p85; AGM7; GRB1; IMD36; p85-ALPHA; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns
数据库入口号Swiss-Prot#P27986
NCBI Gene ID5295
Uniprot
P27986
浓度1mg ml
配方0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存Shipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
应用详情
WB=1:500-2000 IHC-P=1:50-200 IHC-F=1:50-200
Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p11 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.
如果您使用该产品C04630H发表了文章，请通知我们，让我们可以引用您的文献。
et al,Identification of Cytochrome P450 2E1 as a Novel Target in Neuroinflammation and Development of Its Inhibitor Q11 as a Treatment Strategy.
, (2025),
PMID:
40122152
货期15天
