产品详情
产品名称BMPR1B Conjugated Antibody
来源种属Rabbit
克隆性Polyclonal
应用WB, IF
种属反应性Hu Ms
特异性The antibody detects endogenous level of total BMPR1B protein.
免疫原描述Recombinant protein of human BMPR1B.
标记AF荧光素
激发/发射波长AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm
别名ALK6;ALK-6;CDw293
数据库入口号Swiss-Prot#:O00238
NCBI Gene ID:658
Uniprot
O00238
计算分子量57
配方0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
保存Store at 4˚C in dark for 6 months
应用详情
WB: 1:50-1:200
IF:1:50-1:200
Antibodies were purified by affinity purification using immunogen.
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene.
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et al,Enhancing the regenerative effectiveness of growth factors by local inhibition of interleukin-1 receptor signaling. In Sci Adv on 2020 Jun 12 by Ziad Julier, Rezvan Karami, et al..PMID:32582857
, (2020),
PMID:
32582857
1-2 weeks
