产品详情
产品名称Histone H4R3me1 Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC,IF
种属反应性Human;Mouse;Rat
免疫原类型Peptide
免疫原描述A synthetic peptide of human MonoMethyl-Histone H4-R3
基因/蛋白名称Histone H4
标记Unconjugated
别名HIST1H4B;H4/I;H4FI;histone H4;Histone H4;HIST1H4A;HIST2H4A;FO108;H4;H4/n;H4F2;H4FN;HIST2H4
数据库入口号Uniprot:P62805
GeneID:8366
Uniprot
P62805
Gene ID
8366
实际分子量13kDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using MonoMethyl-Histone H4-R3 antibody.
Immunohistochemistry of paraffin-embedded rat testis using MonoMethyl-Histone H4-R3 antibody.
Immunohistochemistry of paraffin-embedded human colon using MonoMethyl-Histone H4-R3 antibody.
Immunohistochemistry of paraffin-embedded mouse brain using MonoMethyl-Histone H4-R3 antibody.
Immunofluorescence analysis of 293T cells using MonoMethyl-Histone H4-R3 antibody.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.
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