产品详情
产品名称Histone H4K20me2 Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC,IF
种属反应性Human;Mouse;Rat
免疫原类型Peptide
免疫原描述A synthetic methylated peptide of human histone H4
基因/蛋白名称Histone H4
标记Unconjugated
别名FO108;H4;H4/n;H4F2;H4FN;HIST2H4;Histone H4;HIST1H4A;HIST2H4A
数据库入口号Uniprot:P62805
GeneID:8370
Uniprot
P62805
Gene ID
8370
实际分子量11KDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using DiMethyl-Histone H4-K20 antibody.
Immunohistochemistry of paraffin-embedded rat testis using DiMethyl-Histone H4-K20 antibody.
Immunohistochemistry of paraffin-embedded mouse testis using DiMethyl-Histone H4-K20 antibody.
Immunofluorescence analysis of 293T cells using DiMethyl-Histone H4-K20 antibody.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.
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