Cas935776-74-2

产品名称JNJ-37822681

别名Dopamine Receptor;DopamineReceptor;D2;JNJ 37822681;JNJ37822681;JNJ-37822681

计算分子量372.34

保存Powder: -20°C for 3 years . In solvent: -80°C for 1 year . Shipping with blue ice.

分子式:C17H17F5N4
Smile:C(C1=CC(F)=C(F)C=C1)N2CCC(NC3=CC=C(C(F)(F)F)N=N3)CC2
DML号:MFCD22580411
纯度:99.48%
溶解度:DMSO:55 mg/mL (147.71 mM)
体内活性:JNJ-37822681 occupied D2 receptors in rat brain at relatively low doses (ED50 = 0.39 mg/kg) and was effective in animal models of psychosis (e.g., inhibition of apomorphine-induced stereotypy or D-amphetamine/phencyclidine-induced hyperlocomotion)[4].
靶点活性:D2:0.39 mg/kg(ED50)
信号通路:G 蛋白偶联受体|神经科学
靶点:Dopamine Receptor