Cas91465-08-6

产品名称λ-Cyhalothrin

别名depolarization;choreoatetosis;acaricide;neurotoxin;pyrethroid;salivation;Parasite;pesticide;Icon;Na channels;Na+ channels;Inhibitor;Insecticide;inhibit;Karate;lambda-Cyhalothrin;α-cyano;λ Cyhalothrin;λCyhalothrin;λ-Cyhalothrin;λ-氯氟氰菊酯;SodiumChannel;Sodium Channel

计算分子量449.85

保存Powder: -20°C for 3 years . In solvent: -80°C for 1 year . Shipping with blue ice.

分子式:C23H19ClF3NO3
Smile:C(=C(/C(F)(F)F)\Cl)\[C@@H]1[C@H](C(O[C@@H](C#N)C2=CC(OC3=CC=CC=C3)=CC=C2)=O)C1(C)C
DML号:MFCD02181175
纯度:99.94%
溶解度:DMSO:60 mg/mL (133.38 mM)
体内活性:The effect of λ-Cyhalothrin (i.p.) on memory, movement activity, and co-ordination in mice exposed to bilateral clamping of the carotid arteries (BCCA) is investigated. Neither memory nor movement co-ordination are impaired by BCCA or λ-Cyhalothrin. Exploratory locomotor activity is markedly reduced in the BCCA/LCH group. Spontaneous movement activity is significantly reduced in the BCCA/λ-Cyhalothrin group . Exposure to λ-Cyhalothrin coexisting with BCCA decreases motor activity in the mice in 2 subsequent 30-min[1].
体外活性:The mechanism of λ-Cyhalothrin toxicity produces delay in sodium channel inactivation resulting in persistent depolarization of the nerve membrane. λ-Cyhalothrin produces membrane depolarization, calcium ion infl ux, and neurotransmitter release from rat brain synaptosomes[1]. λ-Cyhalothrin possesses estrogenic properties and is able to function as a xenoestrogen promoting human breast carcinoma cell proliferation in vitro[1].λ-Cyhalothrin has found multiple uses in pest (fleas, cockroaches, flies, and ants) control[1].λ-Cyhalothrin is highly effective against the malaria transmitting species of Anopheles[1].
信号通路:离子通道|微生物学
靶点:Sodium Channel|Parasite