产品详情
产品名称EIF4A1 (Succinyl-K193) Antibody
来源种属Rabbit
克隆性Polyclonal
纯化The antibody was purified from rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
应用WB
种属反应性Human
特异性EIF4A1(Succinyl-K193) Antibody detects endogenous levels of eIF4A1 only
when succinylated at K193.
免疫原描述A synthesized peptide derived from human eIF4A1 around the succinylated site of K193.
标记Unconjugated
别名eIF-4A-I,eIF4A-I,DDX2A, EIF4A
Uniprot
P60842
Gene ID
1973
实际分子量46kDa
浓度1 mg/ml
配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM
NaCl,0.02% sodium azide and 50% glycerol.
保存Store at --20˚C/1 year
应用详情
Western Blot: 1/500 - 1/2000
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
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