产品详情
产品名称GLUT1(Mono-methyl-K245) Antibody
来源种属Rabbit
克隆性Polyclonal
纯化The antibody was purified from rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
应用WB
种属反应性Human
特异性GLUT1(Mono-methyl-K245) Antibody detects endogenous levels of GLUT1 only
when mono-methylated at K245.
免疫原描述A synthesized peptide derived from human GLUT1 around the mono-methylated site of K245.
标记Unconjugated
别名Glucose transporter type 1, erythrocyte/brain,GLUT-1,HepG2 glucose transporter,GLUT1
Uniprot
P11166
Gene ID
6513
实际分子量54kDa
浓度1 mg/ml
配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM
NaCl,0.02% sodium azide and 50% glycerol.
保存Store at --20˚C/1 year
应用详情
Western Blot: 1/500 - 1/2000
Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake (PubMed:18245775, PubMed:19449892, PubMed:25982116, PubMed:27078104, PubMed:10227690). Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses (PubMed:18245775, PubMed:19449892). Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain (PubMed:10227690). In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors (By similarity).
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