产品详情
产品名称SUCLA2 (Phospho-Ser124) Antibody
来源种属Rabbit
克隆性Polyclonal
纯化The antibody was purified from rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
应用WB
种属反应性Human;Mouse
特异性SUCLA2(Phospho-Ser124) Antibody detects endogenous levels of SUCLA2( only
when phosphorylated at Ser124.
免疫原描述A synthesized peptide derived from human SUCLA2 around the phosphorylation site of Ser124.
标记Unconjugated
别名SUCLA2,A-SCS,SCS-betaA
Uniprot
Q9P2R7
Gene ID
8803
实际分子量50kDa
浓度1 mg/ml
配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl,0.02% sodium azide.
保存Store at --20˚C/1 year
应用详情
Western Blot: 1/500 - 1/2000
ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA (PubMed:15877282). The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit (By similarity).
如果您使用该产品SAB657发表了文章，请通知我们，让我们可以引用您的文献。
et al,OXCT1 succinylation and activation by SUCLA2 promotes ketolysis and liver tumor growth.
, (2025),
PMID:
39862868
Yes
